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Alphamox (Augmentin)
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Augmentin

Alphamox (amoxicillin + clavulanic acid) is widely used in the treatment of odontogenic infection. Therefore, this study is designed to generate data to support its use by demonstrating efficacy, safety and tolerability in comparison with clindamycin in subjects with acute odontogenic infections with or without abscess. This will be a two-arm, parallel, comparative, observer blind, randomised study to assess efficacy, safety and tolerability of amoxicillin + clavulanic acid (875mg/125mg) in comparison with clindamycin (150mg) administered for 5-7 days in subjects with acute odontogenic infections with or without abscess. The study will be performed in adult subjects both male and female ≥18 years of age who present with acute odontogenic infections. A total of 472 subjects will be randomized in 1:1 ratio, i.e. 236 subjects in each treatment arm. The treatment duration of the study will be at least 5 days or maximum 7 days depending upon the treatment response. Subjects will be assessed on Day 5 and if Investigator feels the need of continuing the treatment at Day 5 then treatment will be continued till Day 7. For subjects who do not show treatment response on Day 5, assessments will be performed on Day 7.

Other names for this medication:
Augmentin, Aclam, Aclav, Aktil, Alfoxil, Almacin, Alphamox, Ambilan, Amimox, Amitron, Amixen, Amobay, Amobiotic, Amocla, Amoclan, Amoclane, Amodex, Amohexal, Amoklavin, Amoksiklav, Amoksina, Amoksycylina, Amolex, Amolin, Amorion, Amosine, Amotaks, Amoval, Amovet, Amoxan, Amoxapen, Amoxibeta, Amoxicap, Amoxiclav, Amoxicure, Amoxidal, Amoxidin, Amoxihexal, Amoxin, Amoxinject, Amoxinsol, Amoxipen, Amoxipenil, Amoxiplus, Amoxistad, Amoxival, Amoxsan, Amoxy, Amoxycillin, Amoxydar, Amoxysol, Ampliron, Amylin, Amyn, Anbicyn, Apoxy, Aquacil, Arcamox, Arlet, Aroxin, Atoksilin, Augmaxcil, Augpen, Axcil, Azillin, Bactoclav, Bactox, Benoxil, Betamox, Bimoxyl, Bioclavid, Biofast, Biomox, Biomoxil, Blumox, Borbalan, Cavumox, Cilamox, Cipamox, Clamentin, Clamicil, Clamovid, Clamoxin, Claneksi, Clavam, Clavamel, Clavamox, Clavaseptin, Clavet, Clavinex, Clavipen, Clavor, Clavoxine, Clavubactin, Clavucid, Clavulin, Clavulox, Clavumox, Claxy, Clonamox, Damoxy, Danoxilin, Derinox, Dexyclav, Dexymox, Dimopen, Dispermox, Dolmax, Duomox, Duphamox, Duzimicin, Enhancin, Exten, Fabamox, Fimoxyclav, Flubiotic, Forcid, Fugentin, Fulgram, Geramox, Germentin, Gimaclav, Glamin, Gloclav, Gramaxin, Grinsil, Grunamox, Hiconcil, Himox, Hipen, Hosboral, Hymox, Ibiamox, Imacillin, Imadrax, Imox, Improvox, Julmentin, Julphamox, Jutamox, Kamox, Klamentin, Klamoks, Klavax, Klavocin, Klavox, Klavunat, Largopen, Levantes, Lomox, Longamox, Macropen, Medoclav, Megamox, Megapen, Meixil, Monamox, Moxacin, Moxatag, Moxiclav, Moxilen, Moxilin, Moxin, Moxitral, Moxypen, Moxyvit, Myclav, Natravox, Neogram, Neomox, Nisamox, Nobactam, Noprilam, Noroclav, Novamox, Novax, Odontobiotic, Omacillin, Opimox, Optamox, Pamecil, Panklav, Pasetocin, Pediamox, Penmox, Pinaclav, Pinamox, Polypen, Promox, Promoxil, Ramoclav, Ranclav, Ranmoxy, Ranoxyl, Rapiclav, Remoxil, Remoxin, Remoxy, Respiral, Rimox, Rindomox, Roxilin, Sawacillin, Sievert, Simox, Sinacilin, Spektramox, Stabox, Sulbacin, Supramox, Symoxyl, Syneclav, Synergin, Synermox, Synulox, Taromentin, Topcillin, Trifamox, Ultramox, Vetrimoxin, Viaclav, Widecillin, Winpen, Xiclav, Zoxil,

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The combination of amoxicillin and clavulanic acid comes as a tablet, a chewable tablet, an extended-release (long-acting) tablet, and a suspension (liquid) to take by mouth. The tablets, chewable tablets, and suspension are usually taken at the start of a meal every 8 hours (three times a day) or every 12 hours (twice a day). The extended-release tablets are usually taken with a meal or snack every 12 hours (twice a day). To help you remember to take amoxicillin and clavulanate, take it around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amoxicillin and clavulanic acid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not chew or crush them.

Shake the liquid well before each use to mix the medication evenly.

The chewable tablets should be chewed thoroughly before they are swallowed. The other tablets should be taken with a full glass of water.

The 250 mg and 500 mg tablets of amoxicillin and clavulanic acid contain the same amount of clavulanic acid. Do not substitute two 250 mg tablets for one 500 mg tablet. The 250 mg regular tablet and the 250 mg chewable tablet contain different amounts of clavulanic acid. They also should not be substituted.

Take amoxicillin and clavulanic acid until you finish the prescription, even if you feel better. If you stop taking amoxicillin and clavulanic too soon, or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

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Intriguingly, transgenic expression of Uba5 in the erythroid lineage rescued the Uba5-deficient embryos from anaemia and prolonged their survival, demonstrating the importance of Uba5 in cell-autonomous erythroid differentiation. The aim of the study is to analyze the management of MToP up until the 7th week of gestation in five centres in the CR.

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Effect of treatment with iloprost with or without bosentan on nailfold videocapillaroscopic alterations in patients with systemic sclerosis. Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach. Influenza A Viruses from Overwintering and Spring-Migrating Waterfowl in the Lake Erie Basin, United States. Based on the use of fabrication techniques developed by the silicon microtechnology industry, numerous studies can now be found in the literature analyzing cell behaviour as to various micro- and nano-features such as lines, wells, holes and more. Techniques to reduce the discomfort of paediatric laceration repair.

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To investigate the adequacy of vitamin D status in a South Australian Aboriginal population, and to examine the relationship between serum 25-hydroxyvitamin D (25-OHD) levels and biochemical variables of calcium and bone mineral homeostasis, as well as other factors which may influence vitamin D synthesis, storage and metabolism. Magnesium alterations can have a noticeable effect on the neuromuscular cardiovascular, and metabolic systems.

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Simulation study of complex action potential conduction in atrioventricular node. The nature and origin of binucleate cells in human preimplantation embryos: relevance to placental mesenchymal dysplasia. Refraction, uncorrected (UNVA) and corrected (CNVA) near visual acuities, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, slitlamp evaluation, wavefront aberrometry, photopic and mesopic contrast sensitivity, anterior segment optical coherence tomography, endothelial cell density, and central corneal thickness measurements were assessed preoperatively and at each postoperative visit.

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