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Antara (Fenofibrate)

Long term Antara did not reduce major coronary events but may reduce total CVD events in type 2 diabetes. A 14 d preventive treatment with Antara reduces susceptibility to stroke in apolipoprotein E-deficient mice as well as decreases cerebral infarct volume in C57BL/6 wild-type mice.

Other names for this medication:
Fenofibrate, Tricor, Antara, Antilip, Controlip, Craveril, Einecs, Fenocap, Fenofibrato, Fenogal, Fenoglide, Fenolip, Fenoratio, Fenosup, Fenox, Fibral, Fulcro, Lexemin, Lifen, Lipanthyl, Lipantil, Lipcor, Liperial, Lipicard, Lipidcare, Lipidil, Lipirex, Lipofen, Lipsin, Lofat, Lofibra, Nofiate, Normalip, Normolip, Secalip, Stanlip, Supralip, Tilene, Trigent, Triglide, Trilipix, Trolip, Versamid,

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Antara is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the blood. Build-up of cholesterol and fats along the walls of the arteries (a process known as atherosclerosis) decreases the blood flow and, therefore, the oxygen supply to the heart, brain, and other parts of the body. This increases the risk of heart disease, angina (chest pain), strokes, and heart attacks. Although Antara decreases the levels of fatty substances in the blood, it has not been shown to decrease the risk of heart attacks or strokes. Antara is in a class of medications called antilipemic agents. It works by speeding the natural processes that remove cholesterol from the body.

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The evaluation of exposure with an unbiased job-exposure matrix in studies of the association between exposure and disease had a statistical power close to that expected in practice with a good expert in the large range of practical situations which were investigated. Resistance determinants may persist at low, but detectable, levels for many years in the absence of the corresponding drugs. The use of a 18-kHz piezo-optical birefringence modulator allows measurements of relaxation times down to 5 ms. In the absence of XPA or XPC, deleterious consequences of triplex-induced genomic instability may be averted by activating apoptosis via dual phosphorylation of the H2AX protein. The knockdown of dHO took place in G0/G1-arrested cells posterior to the morphogenetic furrow and thus prevented these cells from entering S-phase, with an increase in the level of histone H2A.V, a DNA damage marker.

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Neither inner cell mass morphology nor embryo grade predicted clinical pregnancy or live birth. This points out the need for a correct surgical management of AAAs and for accurate accomplishment of follow-up programmes supported by ultrasound echography of graft-arterial anastomoses and of the arteries at risk of aneurysmal disease. We set out to study if early-onset androgenic alopecia was associated with an increased risk of prostate cancer later in life.

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Statistical analysis was performed to compare the general QoL with that of the general population. Herpes simplex virus type 1 (HSV-1) infections represent a significant worldwide heath problem. Lipid utilization in radish seedlings as affected by weak horizontal extremely low frequency magnetic field. Enrichment and separation of chlorogenic acid from the extract of Eupatorium adenophorum Spreng by macroporous resin.

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The addition of furfural residues to maize seed production may be considered to be a good strategy for recycling the waste, converting it into a potential resource as organic amendment in arid and semi-arid calcareous soils, and may help to reduce the use of mineral chemical fertilizers in these soils. Outcome of locking compression plates in humeral shaft nonunions. We contend that using aged animals yields insight into aspects of stroke injury and recovery that are masked, or not elicited, in younger animals. Matlab7.0 software was used to calculate the bone volume of alveolar cleft before bone graft and bone bridge volume after bone graft. Extracellular matrix of the central nervous system: from neglect to challenge.

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When glucose oxidase was immobilized in a hydrogel, a dose dependent electrochemical response to glucose was observed. The Communication subscale had the poorest psychometric properties. The portion of the simultaneous masker that made the greater contribution to additional masking was the part that overlapped with the signal, not with the forward masker.

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Accumulating data show that the tyrosine protein kinase Zap-70 plays an essential role in T cell receptor-mediated signal transduction. PredicT-ML: a tool for automating machine learning model building with big clinical data.

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Attention to these process components will facilitate effective interventions by educators in schools. Inorganic carbon-uptake mechanisms in the seagrass Amphibolis antarctica were determined using the carbonic anhydrase inhibitor acetazolamide (AZ) and the buffer tris(hydroxymethyl)aminomethane (TRIS). Dysplastic trapezium is a condition that is characterized by an exaggerated slant (slope) of the distal articular surface of the trapezium in relation to the axis of the second metacarpal. The paper will present the pilot results of the first mobile application (SMAIL) for rapid information sharing on NPSs among health professionals. I regularly see last observation carried forward, assumed worst-case scenario, or some other static imputation method still being submitted and published in journals.

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Platelet-rich plasma (PRP) is used for the treatment of tendinopathy. Ulnar and cerebellar embolization from an ulcerative subclavian artery lesion.

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We also selected five healthy volunteers as the control group and took 11 blood samples. The ED dimensions and JB abnormalities were evaluated with high-resolution computed tomography. This phenomenon is usually associated with an oxidative stress in various settings, but few data are available on cardiac arrest in human.

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To determine the median interpregnancy maternal weight change between first and second pregnancies, and second and third pregnancies and to assess the impact of this weight change on pregnancy outcome in a cohort of women with a macrosomic first delivery. Stroke researchers and clinicians are uniquely suited to provide the facts, figures and statistics to help these officials weigh alternative options, and need to become actively involved in the advocacy efforts of their professional organizations. As a result of the clinical pathway implementation for TUR-P, the length of hospital stay decreased from 17.2 days to 3.8 days and the total medical insurance charges (insurance points) also decreased from 37,484.6 to 31,278.9 yen. Using cultured cardiac endothelial cell (CEC) and in vivo approaches, we show that CECs lacking miR-532 exhibit increased transition to a fibroblast-like phenotype via endothelial-to-mesenchymal transition (EndMT), while CECs over-expressing miR-532 display decreased EndMT.

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Target-lesion revascularization (TLR) and loss of patency remain high following treatment of in-stent restenosis (ISR) of the femoropopliteal (FP) artery. Only smoking cessation and long term oxygen therapy (LTOT) improve survival in COPD. Despite this, the precise details of SL trans-splicing have yet to be elucidated.

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Finally, the conjugation of the BODIPY core has been extended using two distyryl groups, hence providing NIR emitting BODIPY derivatives, in which one or two PEG groups have been anchored, making these systems very promising for future medical imaging applications. Similar results were obtained from mtDNA restriction-site data, although there are some discrepancies, and trees based on both DNA data sets are complicated by evidence for historical and/or ongoing hybridization. Test of cure was achieved in seven patients and confirmed successful eradication. This first study in blood transfusion services in our context was been useful to assess customer satisfaction and identify the main axes on which targeting priority actions in order to effectively use available resources. Total blood haemoglobin concentration is increasingly being used to assess physiological condition in wild birds, although it has not been explicitly recognized how reliably this parameter reflects different components of individual quality.

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Terbinafine in combination with other antifungal agents for treatment of resistant or refractory mycoses: investigating optimal dosing regimens using a physiologically based pharmacokinetic model. Abnormal spindle-like microcephaly associated (ASPM) plays an important role in neurogenesis and cell proliferation. Our experience with the present study highlights the role of mucins in the development and progression of BC. Our approach is formulated in a Minimum Description Length hypothesis selection framework, which allows it to recover from mismatches and temporarily lost tracks. Background selections by melanic forms in various species are interpreted in the light of this conclusion.

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CENTROMERIC INCOMPATIBILITIES IN THE HYBRID ZONE BETWEEN HOUSE MOUSE SUBSPECIES FROM DENMARK: EVIDENCE FROM PATTERNS OF NOR ACTIVITY. Collembola, the biological species concept and the underestimation of global species richness. Two lines of HPV 16-immortalized human endocervical cells (HEN-16 and HEN-16-2) generated from primary cells (HEN) were treated with cigarette smoke condensate (CSC). The present study aimed to more information on this very distinct patient collective.

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Simultaneous electroencephalography (EEG) and magnetic resonance imaging (MRI) may allow imaging of the brain at high temporal and spatial resolution. The tool may be very valuable in preventing false positive identification of patients with epilepsy in EHR-based epidemiologic research. Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is an accessory protein that interacts with a number of cellular and viral proteins. Eighteen-year experience with the Medstone STS lithotripter: safety, efficacy, and evolving practice patterns.

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This study investigated the possible association between this polymorphism (rs1799983) and disease severity in Chinese children with EV71 infection. The various manifestations generated by these compounds can be linked, in part, to different levels of dopamine (measured by HPLC) and degrees of neuronal damage in the basal ganglia and cerebellum. Our results indicate that the synergistic actions of OxyE and OxyL in the double hydroxylation step prevent accumulation of shunt products during oxytetracycline biosynthesis in S. Effects of prenatal ethanol exposure and stress in adulthood on lymphocyte populations in rats.

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Although increasing atmospheric nitrous oxide (N2O) has been linked to nitrogen loading, predicting emissions remains difficult, in part due to challenges in disentangling diverse N2O production pathways. The systolic variation of mitral regurgitation (MR) is a pitfall in its quantification. Rhizobium leguminosarum nodule isolates belonging to three biovars, trifolii, viciae and phaseoli characterized earlier as competitive or uncompetitive relative to native rhizobia, were used.

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MALDI-TOF MS results were concordant with those of sequence analyses of the internal transcribed spacers (ITS1/ITS2) and the D1/D2 domains of the large subunit of the ribosomal DNA. This study aimed to assess acceptability and preferences for the SILCS diaphragm for vaginal gel delivery compared to a prefilled applicator. These defects evolved during the generation of reactive oxygen species which contributed to the antibacterial activity.

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A Molecular Polycrystalline Ferroelectric with Record-High Phase Transition Temperature. Ten patients with an isolated PCL injury in one knee and the contralateral side intact participated in the study.

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2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system. This study characterized the halogen bonds in the CH3I and CCl4 complexes using matrix isolation infrared spectroscopy and density functional theory calculations. MR imaging of bone metastases and choice of sequence: spin echo, in-phase gradient echo, diffusion, and contrast medium.

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In conclusion, the results indicated that tumstatin induced apoptosis that is mediated by the Fas signaling pathway in SCC-VII cells and inhibited tumor growth in an SCC-VII animal model. Invasion of the great vessels or atrium was statistically significant prognostic factor for PFS.

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1.55 A structure of the ectoine binding protein TeaA of the osmoregulated TRAP-transporter TeaABC from Halomonas elongata. Here, we reconstructed three-dimensional cryo-EM structures of two GFP-tagged RyR2s with GFP inserted after residue Glu-310 and Ser-437, respectively. Pathogenicity of PMV-3/Turkey/England/Midland poultry holdings/1981 for chickens and turkeys. Furthermore, 3F7 also interfered with BK-driven edema in the severe swelling disorder hereditary angioedema (HAE) type III.

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Pathogens isolated from deep soft tissue and bone in patients with diabetic foot infections. Therefore, effects of aging and superfusion on tissue protein image texture were compared. Blood samples were obtained at entry and at the end of the military service, and during each episode of respiratory infection to measure antibody responses against 10 viral and 2 bacterial pathogens.

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We proposed that the intron 5 of LMBR1 was presumably subject to balancing selection during the evolution of modern human. Are endothelial damage and inflammation level demonstrated clearly in liver transplant patients? Pediatric laryngeal papillomatosis: our experience (three cases) Cellular traction force recovery: An optimal filtering approach in two-dimensional Fourier space.

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Children whose parents smoke, and among them particularly children from socially disadvantaged families, should be recognised as key target groups when implementing future tobacco-control measures. Furthermore, the cHP, which is predicted to be conserved among arthropod-borne flaviviruses, is required for WNV replication. Our goal was to assess the usefulness of spirometry to estimate the risk of pneumothorax in patients undergoing percutaneous needle biopsy with CT guidance for solitary pulmonary nodule (SPN).

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We describe how LEX facilitates active movement of the leg, and thereby increases venous flow in the lower extremities. Understanding how individual neurons integrate the thousands of synaptic inputs they receive is critical to understanding how the brain works.

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Pretherapy tumor biopsies were studied by PCR for human papillomavirus type 16 and linked to OS, progression-free survival (PFS) and demographics. Community-based research: a tool for community empowerment and student learning. Malignant melanoma in the esophagus is a rare condition which has been described only occasionally in case reports or in larger series of patients with esophageal disease. A clinical trial, using historical controls and involving current ICU patients who had acquired nosocomial pneumonia, was carried out from June of 2002 to June of 2003. These transfers are controlled by both the surfactant system (micellar transport), and the partial solubility of one phase in another (molecular transport).

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The proposed schemes are tested against the Forward Additive Lucas-Kanade and the Simultaneous Inverse Compositional (SIC) algorithm through simulations. K214A coupled to PI metabolism through both PTX-sensitive and PTX-insensitive G proteins. Toll-like receptor 2 (TLR2) and TLR4 genes play critical roles in host recognition of Mycobacterium bovis infection and initiation of innate and adaptive immune response. The absorption band of FS1 at 480 nm is significantly enhanced only when both SDS and Na(2)SO(4) are the input at high concentrations, in accordance with an AND logic gate. In a second experiment, ovariectomized female hamsters were given (i) repeated aggressive experience, (ii) a single aggression test or (iii) no aggression test.

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Nitroglycerin is a prototypic NO-donor, and triggers migraine in humans. This suggests that therapeutic modulation of the microbiome may contribute to management of celiac disease. Deployed service personnel who were in a relationship, and who had children, completed a survey while deployed on combat operations.

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We report two cases of superior gluteal artery aneurysms successfully treated with coil embolization and review treatment options for these lesions. This study was aimed to evaluate the Weiss system to diagnose ACCs and to compare it with TNM staging. Because glutamine is an important precursor for nucleic acids biosynthesis, we hypothesized that GS is preferentially expressed in the crypt region, which contains the rapidly proliferating cells in the small intestine. Cell polarity establishment and maintenance depends upon the three complex proteins which are par, crumbs and scribble complexes, of which are reported as tumor suppressors. Innovative approaches for antagonism of tumor-associated regulatory T-cell infiltration and redirection of self antigen-driven regulatory T-cell activation may provide the key to development of future strategies for cellular immunotherapy against ovarian cancer.

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Herein we report the first case of a perforated ulcer complicated by peritonitis caused by R. To elucidate the function of Fh3GT1, RNA interference vector (pART-Fh3GT1i) was constructed, and introduced into Petunia grandiflora by Agrobacterium-mediated transformation. Prophylaxis with sucralfate is associated with a lower rate of nosocomial pneumonia and mortality, providing strong evidence for use of this agent in clinical practice.

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For each patient, considerations on the underlying pain mechanisms, immediate and potential long-term side effects, and price as well as comorbidities and concurrent medications will decide which drug should be the first choice, but until further progress is made towards a mechanism-based classification, treatment is likely to be a trial-and-error process where drug combinations may also be considered. Respondents in a 6-wave longitudinal mail survey completed questionnaires before September 11, 2001, and again in 2003 and 2005. We performed a GRADE evaluation of the quality of evidence for interventions. The included trials in the updated review involved eight unrelated treatments and included many disparate measures of neuropathy, resulting in insufficient data for any one measure to combine the results in most instances. Comparison of Methods to Obtain Force-Field Parameters for Metal Sites.

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Here, a comparative protein expression profiling of catecholamine biosynthesis enzymes and detoxification enzymes was conducted in WM35 melanoma cells and in HEK epithelial cells, in comparison with normal human melanocytes. These features include the geometry, size, and orientation of the stimulating sites, proximity of the device to spiral ganglion neurons, shape and position of the insulating carrier, and the stimulation mode (monopolar, bipolar, etc.). HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus. LncRNA TUBA4B is recently identified to be a critical mediator in non-small cell lung cancer.

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Inhibition of Ras-GTPase signaling by FPTIII ameliorates development of cardiovascular dysfunction in diabetic-hypertensive rats. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins.

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We extracted patient-related, physician-related, cost, time and follow-up outcomes. Diabetic nephropathy (DN) is a complex and chronic metabolic disease that evolves into a progressive fibrosing renal disorder. Our results suggest that this may be a useful supplement to condom use, particularly among couples who experienced condom failures previously. This study supports findings from other European studies that generally demonstrate modest public awareness of many established cancer risk factors. The dependence of the ice-albedo feedback on atmospheric properties.

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Human resources in healthcare are not readily available, particularly in the area of respiratory disease specialists. Recordings were analysed visually for recurrence of phase III of the migrating motor complex, and a validated computer program was used to calculate the incidence and amplitude of contractions. It is hypothesised that the growth hormone (GH) target STAT5b maintains mucosal barrier integrity by promoting CEC survival and inhibiting NF-kappaB activation. Importantly, MGCD arrested cell cycle at mitosis (M) phase with formation of multipolar spindles, which was associated with activated p53-mediated postmitotic checkpoint pathway to induce apoptotic cell death.

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We studied retrospectively 11 cases enrolled in the pediatrics department of Sousse during 10 years period (1993-2002). In an attempt to answer this question, we have modeled the sarin-inhibited AChE reactivation by duzela 20 mg used car other nucleophiles (with and without the so-called alpha-effect) by applying the B3LYP/6-311G(d,p) level of theory. Therefore, it is essential to correlate the clinical findings with electromyographic recordings and dopamine transporter scan (DaT). Electrical activity is abundant in early retinal development, and electrical stimulation has been shown to modulate embryonic stem cell differentiation towards a neuronal fate.

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Developing a local antimicrobial resistance action plan: the Cornwall One Health Antimicrobial Resistance Group. Ecological niche partitioning between Anopheles gambiae molecular forms in Cameroon: the ecological side of speciation. Our clinical experience revealed that CPC was safe, nonabsorbable, and effective. Uranium-lead data indicate that the high-pressure granulitic and charnockitic nuclei within the medium-grade metamorphic complex of the Peruvian coastal area must be related to que es levedad deserres art store an orogenic event 2 x 10(9) years ago. The association was estimated using logistic regression analysis.

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Effects of a beta-lactamase inhibitor, sulbactam, on the activity of carbapenems against Pseudomonas aeruginosa. We report on the clinical, imaging-including ultrasound, computed tomography, and acitop ointment magnetic resonance imaging-and histological features of a fibroma of the tendon sheath with mineralized chondroid and osseous metaplasia, presenting as a semimembranosus bursitis. Obesity and psychological wellbeing in patients undergoing fertility treatment.

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In simulation studies, we demonstrate the power gain from using both the prior biological information and variance signals compared to using either of the two or neither information. Ten new species of demosponges, assigned to the orders Poecilosclerida, Axinellida victadol tab hunter and Dictyoceratida, discovered in the Gulf of Alaska and along the Aleutian Island Archipelago are described and compared to relevant congeners. LCS provides for the rapid phenotypic analysis of loss-of-function mutations, circumvents the need for germ-line transmission of null alleles, and, most significantly, facilitates the study of essential genes whose inactivation is associated with early lethal phenotypes.

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Extended and saturation prostatic biopsy in the diagnosis and characterisation of prostate cancer: a critical analysis of the literature. Studies evaluated the quantitative impact of structural interventions for the prevention of male-to-female IPV in LMIC through (a) IPV incidence or prevalence or (b) secondary outcomes theoretically linked to IPV by study authors. The dose to the lung dominated the committed effective dose, with the lung absorption parameters, particularly the slow dissolution rate, ss, dominating the overall uncertainty. Using a flexible alternative based on the beta distribution and a compiled data set of mammalian survivorship curves for 58 species, we explore the influence of survivorship shape and scale on the metronex gel for teeth estimation of r.

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We evaluated the predictive value of these vascular biomarkers for cardiovascular disease (CVD) events in patients with rheumatoid arthritis (RA): aortic pulse wave velocity (aPWV), augmentation index (AIx), carotid intima-media thickness (cIMT), and carotid plaques (CP). Docetaxel-based chemotherapy in elderly patients (age 75 and older) with castration-resistant prostate flutamide hirsutism side effects cancer. Our instrument will find application in the study of nuclear atomic phenomena.