Digene is used to treat damage from gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 5 years of age and older. Digene is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. It is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Digene is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.

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In order to achieve therapeutic activity, drug release from the liposomes must occur at a rate sufficient to achieve therapeutic concentrations of drug at the cellular target. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction. Job satisfaction and work related variables in Chinese cardiac critical care nurses. WE RETROSPECTIVELY ANALYZED VARIOUS CHARACTERISTICS OF SMALL CELL BLADDER CARCINOMA: patient demographics, histological diagnosis, disease stage, treatment effects and outcome, in 14 non-metastatic small cell bladder carcinoma patients treated at our institution between 1995 and 2006.

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Effects of hemin on heme oxygenase-1, gastric emptying, and symptoms in diabetic gastroparesis. To characterize local field potentials, high frequency oscillations, and single unit firing patterns in microelectrode recordings of human limbic onset seizures.

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Fuzzy synchronization likelihood with application to attention-deficit/hyperactivity disorder. D-CECaT as preoperative chemotherapy for unresectable neuroblastoma in children over one year of age. The most important advancements in the Cardiorenal syndrome (CRS) are its definition and subsequent classifications.

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Synaptic connectivity was increased in the NPC and combined treatment groups. This corresponds to a field approximately 8 G in the rotating frame per ampere of coil current. Due to the variation in the balance between adhesion and centripetal forces, cancerous and normal cells demonstrate clearly distinctive distributions of the fluorescent particles adherent to the cell surface over the culture dish. Recent studies have highlighted the importance of CTIP2 in several other pathologies, such as cardiac hypertrophy and various types of human malignancies.

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The calculated results and subsequent analysis excluded enol-OxyLH2, keto-OxyLH2, and enolate-OxyLH(-) as possible light emitters. The risk of maternal and placental complications in pregnant women with asthma: a systematic review and meta-analysis.

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We aimed to determine the incidence and prognostic implications of non-enhancing cortical signal abnormality in glioblastomas. Admission of a family member to an intensive care unit (ICU) is a deeply distressing and often unexpected life event to the family. Community social capital and suicide mortality in the Netherlands: a cross-sectional registry-based study. parasite, hepatitis A virus (HAV), and norovirus (NoV) contamination in mussels collected from 8 stations in the inner, middle, and outer regions of the Gulf of Izmir. Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy.

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Hence, we developed an intermediate workflow to streamline potential urinary biomarkers of prostate cancer (PCa). Anthropometric values were measured and sociodemographic data obtained using a questionnaire. Sleep-dependent synaptic down-selection (I): modeling the benefits of sleep on memory consolidation and integration. For example, Neisseria meningitidis engages these human receptors via outer membrane proteins of the colony opacity-associated (Opa) protein family triggering internalization into non-phagocytic cells. Locomotor kinematics predicts functional gait, and the magnitude of variability and local instability should be calculated to fully evaluate locomotor system health.

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The findings suggest that Bax may be one of the mediators of radiation-induced apoptosis in vivo. We are rather in favor of an integrative approach and a global treatment on a case by case basis.

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To investigate the association of arginine methylation with myocardial function and prognosis in chronic systolic heart failure patients. Pretreatment of sinus aspirates with dithiothreitol improves yield of fungal cultures in patients with chronic sinusitis. To investigate the involvement of enthesis and its correlation with clinical and quality of life parameters in patients with spondyloarthritis (SpA). Efficacy of the stranger safety abduction-prevention program and parent-conducted in situ training. Scores on part 1 were moderately and positively correlated with part 2 and with frequency of participation.

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Gastric blood flow was determined using laser Doppler flowmetry. We are able to dissect the whole chromatin into two types of chromatin domains which have clearly different Hi-C contact patterns as well as different sizes of chromatin loops. Taurine Biosynthesis in a Fish Liver Cell Line (ZFL) Adapted to a Serum-Free Medium.

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The feature set includes both baseline-independent and baseline-dependent features. In the present study we analyzed 12 physical parameters, namely force, static and dynamic balance (both quantified by means of 4 parameters each), rapidity, visual reaction times and acoustic reaction times, over 185 subjects.

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Total joint arthroplasty is a large and growing part of the U.S. A large number of life-events perceived as having a negative impact on quality of life may indicate chronic stress, and the results of our study indicate that stress may reduce the chances of a successful outcome following IVF, possibly through psychobiological mechanisms affecting medical end-points such as oocyte retrieval outcome. The technique is safe, effective and accurate for biopsy and provides a surgical route that can be added to the armamentarium for the management for pathological conditions in this region.

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We evaluated the use of laparoscopic suture rectopexy (LSRP) as a modality of treatment for rectal prolapse in children. Strategies for common challenges such as poor visualization and renal transplant mobility are addressed.

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Pulmonary oedema in self-contained underwater breathing apparatus diving is an accident whose risk factors, conditions of occurrence and incidence are not well-known. Analgesia, sedation and arousal status in burn patients: the gap between recommendations and current practices.

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Many of these agents are in their infancy stages and only beginning to make their mark on lymphoma treatment while others have begun to show promising efficacy in relapsed disease. Insulin resistance increases loss of antibody to hepatitis B surface antigen in nondiabetic healthy adults.

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Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors. Based on rigorous calculations for optimized sawtooth-shaped and binary-multilevel blaze profiles, we deduce a semianalytical model describing the shadowing phenomenon for the general case of oblique incidence. Therefore, we aimed to investigate how ticagrelor could impact the distribution of cholesterol and consequently alter the organization of lipid rafts on platelet plasma membranes. Microglial cells play an important role during neuroinflammation in the central nervous system.

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Parents reported on clinician use of the decision aid and the amount of shared decision making and uncertainty they experienced. Hydrothermal carbon spheres containing silicon nanoparticles: synthesis and lithium storage performance. The HECT-binding domain of Smad7, which activates Smurf2, antagonizes this inhibitory interaction. The increase in contractile activity after intestinal transection/reanastomosis is secondary to an increase in frequency of contractions and not amplitude. Hybrid vector including polyethylenimine and cationic lipid, DOTMA, for gene delivery.

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Acute febrile polyarthritis and prolonged inflammatory syndrome in a patient with acute hepatitis A The patellar tendon was successfully reconstructed with autogenous semitendinosus and gracilis tendon graft.

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As a consequence, a miniaturized implantable sensor and data logger were developed and applied experimentally in a porcine model to measure suture tension dynamics after laparotomy closure. Furthermore, this trajectory shows increasing areas for each data cluster, with a highly compact cluster for the early adulthood healthy group at one end and a widely spread cluster for the late adulthood osteoarthritic group at the other end. Use of variable p(H) interface to a mass spectrometer for the measurement of dissolved volatile compounds.

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African Dacus (Diptera: Tephritidae: molecular data and host plant associations do not corroborate morphology based classifications. The documentation form consists of numerous sections to collect information on: (a) Type of population (children, adult, elderly or pregnant) (b) poisoning agents (c) route of exposure (d) type of poisoning (intentional, accidental or environmental) (e) demographic details of patient (age, gender and bodyweight) (f) enquirer details (background, place of call and mode of request) (g) category and purpose of query and (h) details of provided service (information provided, mode of provision, time taken to provide information and references consulted).

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Honey is a natural substance produced by honeybees and has nutritional and therapeutic uses. Incubation time for enzyme-substrate reaction for maximum enzyme activity was increased from 15 minutes to 60 minutes in case of immobilized enzyme. The surface was also covered with boulders and bright streak-like markings analogous to base-surge or ejecta cloud deposits. Combination of a new oral anticoagulant, aspirin and clopidogrel after acute coronary syndrome: new therapeutic standard?

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Transient receptor potential (TRP) channels expressed on nociceptors respond to different sensory stimuli and a few of them have been studied previously in the models of neuropathic pain. In this study, we estimated whether 67LR was constitutively over-expressed in high-grade astrocytomas by immunohistochemical staining and Western blotting, and investigated the role of a low level of 67LR expression in glioma cell line-U251 by constructing an interfering RNA expression plasmid. Trends in Pediatric and Adolescent Anterior Cruciate Ligament Injuries in Victoria, Australia 2005-2015. Morphological evaluation of dysmyelopoiesis in decitabine-treated patients with myelodysplastic syndromes To implement a fast method for measuring psychophysical tuning curves (PTCs) for use in clinical applications, such as assessment of frequency selectivity and detection of dead regions in the cochlea.

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In other stages, there were improved outcomes in negative and positive symptoms and general psychopathology. It is characterized by marked shortening of the long bones with severe platyspondyly and dumbbell-shape metaphyses. THE WORK DONE BY THE GERMAN SUBCOMMITTEE ON THE TEACHING OF MATHEMATICS.

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Here, I show that the distinctions among them arise from the ways in which fitness is partitioned: none can be drawn when the fitness consequences of an action are wholly aggregated, but they manifest clearly when the consequences are partitioned into primary and secondary (neighbourhood) effects. Inhibition of the mitotic exit network in response to damaged telomeres.

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A recombinant strain of Saccharomyces cerevisiae, containing a 2-microns-fragment-based plasmid (pYE alpha a4) was grown under non-selective conditions in continuous culture. Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. However, it is still unclear whether these changes are related to cognitive deficits, which have been described in ET patients. The chicken leukocyte receptor complex encodes a family of different affinity FcY receptors. The promoter region of BmTf has numerous putative NF-kappaB binding sites, suggesting its possible function in innate immunity.

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The reaction is proposed to proceed through a photoredox-promoted generation of an electrophilic arylgold(III) intermediate that undergoes transmetalation with allyltrimethylsilane to form allylarenes. To present totally ultrasonography-guided percutaneous nephrolithotomy (PCNL) in the flank position, its preliminary results, and the practical considerations. In the staging of locally advanced bladder cancer and localized prostate cancer 22 consecutive patients underwent open pelvic lymphadenectomy and 9 consecutive patients underwent laparoscopic pelvic lymphadenectomy.

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Although most of these showed lower FD-factors, in particular, the coconut/dill-like smelling wine lactone ((3S,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one) appeared with a quite high FD factor. Mitochondrial DNA rearrangements in health and disease--a comprehensive study. Healing of localized gingival recessions treated with a coronally advanced flap alone or combined with an enamel matrix derivative and a porcine acellular dermal matrix: a preclinical study. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs. Ligamentous knee injuries are common and costly, both in financial terms and time missed from work and recreational activities.

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Data from a previous study of soldier driving postures and seating positions were analysed to develop statistical models for defining accommodation of driver seating positions in military vehicles. In particular, I consider the problem of multilocus IBD probability for relative pairs, k siblings, and a group of pedigree members. Furthermore, we present a fast, sensitive, and specific soil toxicity test which enhances traditional tests and may help to improve current environmental risk assessments and monitoring of potentially polluted sites. In the other diet groups, there was no difference in state 3 respiration between the hibernating and summer active groups. Functional Outcomes and Delayed Cerebral Ischemia Following Nonperimesencephalic Angiogram-Negative Subarachnoid Hemorrhage Similar to Aneurysmal Subarachnoid Hemorrhage.

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An excessively high viscosity results in higher residues, besides succeeding in slowing down the bolus flow. Nanoscale protein architecture of the kidney glomerular basement membrane. The main mechanical properties were all significantly changed after mixing beta-TCP into the SR matrix, except for tearing strength. Serum clearance and urinary excretion of pteroylmonoglutamic acid in gestating and lactating dairy cows.

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Present evidence-based recommendations on the use of biochemical markers of bone turnover in the management of osteoporosis. On the Computation of Adiabatic Energies in Aza-Boron-Dipyrromethene Dyes. Assessment of GSK1904529A as a promising anti-osteosarcoma agent.

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Disentangling mechanisms involved in collagen pyridinoline cross-linking: The immunophilin FKBP65 is critical for dimerization of lysyl hydroxylase 2. Taken separately, these criteria were not sufficient to recognize patients with schizophrenia, an algorithm should be based on all of them. At 3-month and 1-year postintervention, staff reported higher levels of knowledge, attitudes, and confidence in managing disruptive behaviors. Aripiprazole joins the family of second-generation mood stabilizers. BALB/c mice were immunized with phosphorylcholine conjugated to keyhole limpet hemocyanin (PC-KLH) and simultaneously treated with 1 microgram recombinant murine IL-12 for 3 consecutive days.

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Selection and efficacy of self-management strategies for dysmenorrhea in young Taiwanese women. This study was designed to determine if hearing status monitoring during intravenous infusion of EA reduces individual variability and to evaluate the correlation between EA dose and Bwt. Oral dextran sulfate sodium induces weight loss, diarrhea, peripheral neutrophilia, and colonic damage. Moreover, the content of hydroxycinnamic acid derivatives and the majority of volatile compounds decreased as the dose of fiber increased. All patients with stage II to IV ovarian cancer who were admitted for bowel obstruction greater than or equal to 6 months after cancer diagnosis from 2000 to 2011 were identified from the Surveillance, Epidemiology, and End Results registry-Medicare database.

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The Use of Stramonium for the Rigidity and Drowsiness Following Encephalitis Lethargica. This paper reviews in vitro and in vivo data that suggest beta-blockers have primarily an anabolic effect on bone metabolism. Lemna minor, the so-called common duckweed, is a model system of these aquatic plants for ecotoxicological bioassays, genetic transformation tools and industrial applications. Human papillomavirus is the most common sexually transmitted disease in the United States.

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The VNT is superior in sensitivity and specificity and is therefore considered the gold standard serological assay. Given the range of HBV DNA levels observed, further studies are warranted to determine its clinical significance and to guide screening strategies and ART selection in these patients. Association between polymorphisms of fat mass and obesity-associated gene and metabolic syndrome in Kazakh adults of Xinjiang, China.

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A common-sense approach to investigation at the primary care level is outlined. Treatment for both conditions needs to be individualized to the clinical presentation. While the sequence of V3 is variable, its length is highly conserved.

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Determining and interpreting new predictive rules for breast cancer familial inheritance. Prostaglandin E2 for local application has been widely used for preinduction cervical ripening in cases presenting with an unfavorable cervical state. The case presented is of a 37 weeks pregnant with history of previous cesarean section. Analysis of argon-38 and argon-39 produced by cosmic rays in four iron meteorites gives normal amounts of the radioactive product argon-39 and abnormally low amounts of stable argon-38. Patients with non-AD neurodegenerative diseases did not show a significant decrease in CFU-EPC levels.

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We, therefore, conclude that, in order to assess the states of health of muscle tissue, it is advisable to rely on three-dimensional morphological measures rather than on the traditional two-dimensional measures. We also recommend taking into consideration the comorbidity between dyslexia and ADHD as an argument in favour of pharmacological intervention in patients with apparently mild symptoms of ADHD.

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PubMed, EMBASE, Cochrane Library, Clinical Trials Register Centers, and Google Scholar were comprehensively searched. According to a web search on recent studies published in Italy on minimally invasive thoracic surgery along the last 3 years, uniportal, nonintubated, and robotic VATS as well as VATS lobectomy have been found to represent the most frequently investigated issues. Extreme diabetic lipaemia associated with a novel lipoprotein lipase gene mutation. Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats. Oral contraceptive pills (OCPs) might reduce ACL injury risk, although the literature appears controversial.